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Chemistry Seminar

May 8, 2014
Room 114, Smith Hall 11:00 a.m.

Ms. Anna Steban

Multifunctional Magnetic Nanoparticles for Targeted Drug Delivery

Advances in new multidisciplinary nanotechnology in combination with exploratory medical research have resulted in magnetic nanoparticles having the potential to be used for many medical purposes including targeted drug therapy. Pharmaceutical species can be guided by magnetic fields to the specific target site of tumor cells using magnetic nanoparticles as a transport mechanism. The use of nanotechnology is increasing in importance as research in cancer therapy is advancing. In the research presented, mice were injected with magnetic nanoparticles, synthesized in aqueous solution and oxidized through aeration, combined with enhanced green fluorescent proteins. A magnet was tied to the mouse near the desired targeted tumor cells. Using transmission electron microscopy and whole-body fluorescent imaging, the results show the nanoparticles concentrated in the desired region. Applications of nanotechnology in the future will vary from water decontamination, communication devices, disease treatment, as well as many other scientific uses.