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Scholars Day 2006, Wednesday, April 12

What Good is the Zebrafish?

The zebrafish, Danio rerio is a popular model system for developmental biologists because embryos are fertilized outside of the body, and organ development can be directly observed. The zebrafish is also a popular model system for human disease. For example, the zebrafish heart responds to drugs similarly to the human, and the effects of compounds on zebrafish cardiac performance is currently being used in toxicity screens for drug development. The broad objective of my research laboratory is to develop and validate a zebrafish-based model system for gastrointestinal physiology. The laboratory breeds and maintains zebrafish, and utilizes several approaches to quantify GI function, characterize the zebrafish cellular anatomy, and to determine the molecular components of the GI tract. An general overview of the zebrafish as a model system will be presented, as well as the specific applications currently underway in the laboratory.

Presenters: Stephanie Gross (Undergraduate Student)
Stacey Hess (Graduate Student)
Scott Leddon (Graduate Student)
Kyle Leonard (Undergraduate Student)
Adam Rich (Faculty)
Topic: Biological Sciences
Location: 216 Hartwell
Time: 9:15 am (Session I)

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