Palladium-catalyzed reactions of aryl chlorides include carbon-carbon, carbon-nitrogen, and carbon-oxygen bond forming reactions, as well as hydrodehalogenation. The work that will be described explores several aspects of the amination and hydrodehalogenation reactions of aryl chlorides using palladium catalysts with biphenyl ligands (developed by the Buchwald group). In hydrodehalogenation reactions, the chlorine substituent is replaced with a hydrogen, while in the amination reaction, the chlorine is replaced with an amine. First, studies of both reactions were done to determine whether the active catalyst is homogeneous, or instead exists as nanoparticles. An understanding of the mechanism could be used for applications of the chemistry to, for example, PCB remediation. A second area of study is the use of ionic liquids as the solvent for these reactions, replacing organic solvents that produce waste that is harmful to the environment. Our results in both of these areas will be described.
|Presenter:||Cory Charbonneau (Undergraduate Student)|
|Time:||10:45 am (Session II)|