Cancer is the second leading cause of death in the United States. Currently, there are very few cancers that can be cured or successfully treated. In many cases, the mitogen-acitvated protein kinase signaling pathway is upregulated in cancerous cells. The MAPK pathway is responsible for carrying extracellular signals to the nucleus in order to control fundamental cellular processes such as growth, proliferation, differentiation, and apoptosis. The goal of my Honors thesis project is to explore potential targets for cancer drugs in this pathway. Ras seems to be a promising target as it is early in the pathway and is implicated in a large number and variety of cancers.
|Presenter:||Michele Sanford (Undergraduate Student)|
|Time:||10 am (Session I)|